Vacation homes involve an awful lot of work. Between guests the house will need a thorough scrubbing, window washing, yard work, and laundry done. In Florida, the pool will need cleaning.
Someone will have to take reservations and meet the guests to give them the keys, and be there to inspect for damage when guests move out.
Since stays are short term, that all has to be done once a week, Because of the work load, hired managers are expensive and if you are not there to do it yourself, you will need to pay a maid service and a gardener.
Yes, I do know people who are making a living by owning vacation rentals. So it can be done. Just make sure you know what you are getting into.